Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4

doi:10.1126/science.1202947

DOI: 10.1126/science.1202947 ISSN:

Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4

Omar S. Qureshi, Yong Zheng, Kyoko Nakamura, Kesley Attridge, Claire Manzotti, Emily M. Schmidt, Jennifer Baker, Louisa E. Jeffery, Satdip Kaur, Zoe Briggs, Tie Z. Hou, Clare E. Futter, Graham Anderson, Lucy S.K. Walker, David M. Sansom

Multidisciplinary

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An inhibitory T cell receptor acts by stripping activating ligands off dendritic cells.

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