DOI: 10.4103/apc.apc_66_26 ISSN: 0974-2069
Trans-2,3-enoyl-CoA reductase-like-related catecholaminergic polymorphic ventricular tachycardia in a child: Clinical course and management outcomes
E. K. Kulbachinskaya, A. A. Pushkov, V. V. Bereznitskaya, I. S. Zhanin, K. V. Savostyanov, I. A. KovalevABSTRACT
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare but potentially fatal inherited arrhythmia. We report a 7-year-old child with CPVT associated with a homozygous trans-2,3-enoyl-CoA reductase-like c.730 + 1G>C variant. To our knowledge, this variant has not been previously reported in the indexed peer-reviewed literature. Prophylactic implantation of an implantable cardioverter defibrillator before symptom onset proved lifesaving during a subsequent ventricular fibrillation episode despite beta-blocker therapy.