Tranexamic Acid-Induced Seizure After Cardiopulmonary Bypass: A Case Report

Tranexamic acid (TXA) is a risk factor for perioperative seizures following cardiac surgery. However, its clinical diagnosis is difficult because these signs are masked by anesthetics and muscle relaxants. In this case, a direct temporal association between high-dose TXA administration and seizure onset was confirmed using intraoperative electroencephalography (EEG) and central venous oxygen saturation (ScvO ₂ ) changes.This case demonstrates that seizures can be triggered immediately after high-dose TXA administration and highlights the importance of integrated assessment of continuous EEG and ScvO ₂ for the early detection of subclinical seizures. This allows for prompt intervention and may lead to better neurological outcomes.