DOI: 10.1097/sap.0000000000004815 ISSN: 0148-7043

The Rise of Nerve Transfers

Pooja Dhupati, Jonathan Jeger, Sunny Vansdadia, Megan L. Anderson, Camryn S. Payne, Olachi Oleru, Shelley S. Noland

Background:

Nerve transfers have been heralded as a “quantum leap” in peripheral nerve surgery, fundamentally altering the reconstructive paradigm over the past 2 decades. This study analyzed national trends in adult traumatic brachial plexus injury (BPI) management, tracking specialty-specific adoption of nerve transfers and comparing 30-day postoperative outcomes with traditional reconstruction.

Methods:

Data were extracted from the National Surgical Quality Improvement Program (2006 to 2022). Adult patients (18 years or older) with a primary BPI diagnosis, who underwent nerve reconstruction, were included. Cases were categorized by the presence of a nerve transfer using CPT code 64905. Analyses included descriptive statistics, standardized mean differences, and multivariable logistic regression.

Results:

Among 544 BPI patients, 80 underwent reconstruction involving a nerve transfer. Plastic surgeons performed 60% of nerve transfers despite accounting for only 33.5% of all BPI reconstructions. Neurosurgeons had the lowest overall nerve transfer utilization but increased to a rate matching orthopedic surgeons in the final 4 years. Nerve transfers were associated with lower 30-day complication rates than traditional reconstruction (2.5% vs. 11%, P =0.034), despite being performed on patients with higher preoperative morbidity risk. In multivariable analysis, orthopedic and neurosurgeons remained significantly less likely than plastic surgeons to perform nerve transfers (OR: 0.26, P <0.001; OR: 0.18, P <0.001, respectively).

Conclusion:

Nerve transfer use in BPI reconstruction has increased steadily, with a recent increase among neurosurgeons. Despite being used in higher-risk patients, nerve transfers were associated with significantly lower short-term complication rates. These findings support continued adoption of nerve transfers and highlight their favorable safety profile.

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