The regulation of stem cell fate and its application in neural regeneration

Abstract

Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and tissue engineering, which involves the comprehensive effect of many factors. The commonly used types of SCs were summarized, and the research progress of regulating the fate of SCs through physical factors, biological factors and chemical factors were discussed. It also reviewed the applications and mechanism of SCs in repairing neurodegenerative diseases, optic nerve injury, auditory nerve injury, traumatic peripheral nerve injury, etc. Finally, the future regulatory strategies and development were prospects. The aim is to provide a new idea and method for the treatment of neural regeneration.