DOI: 10.1126/science.1199498 ISSN:

The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling

Peggy P. Hsu, Seong A. Kang, Jonathan Rameseder, Yi Zhang, Kathleen A. Ottina, Daniel Lim, Timothy R. Peterson, Yongmun Choi, Nathanael S. Gray, Michael B. Yaffe, Jarrod A. Marto, David M. Sabatini
  • Multidisciplinary

A search for substrates of a growth-promoting kinase revealed a regulatory feedback loop involved in tumor suppression.

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