DOI: 10.1039/d5ma01389e ISSN: 2633-5409
The influence of H-bonding network disruption on morphology, structure and autofluorescence of amyloids
Manuela Grelich-Mucha, Ana Maria Garcia, Vladimir Torbeev, Joanna Olesiak-BańskaAn amide-to-ester modified analogue of an amyloidogenic peptide forms spherical aggregates instead of amyloid fibrils, while retaining autofluorescence at 412 nm. This behavior is attributed to proton transfer between ionised N- and C-termini.