DOI: 10.32322/jhsm.1963841 ISSN: 2636-8579

The impact of body-mass index on new metabolic indices between classical and nonclassical phenotypes of polyendocrine metabolic ovarian syndrome (PMOS)

Şerife Ezgi Doğan, Özge Yücel Çelik
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Aims: The purpose of this study is to identify relationship between new metabolic indices -namely Triglyceride Glucose Index (TyG), lipid accumulation product (LAP), and Visceral Adiposity Index (VAI) are investigated-and classical and nonclassical polyendocrine metabolic ovarian syndrome (PMOS) phenotypes.Methods: Data were evaluated retrospectively which collected from 103 patients with PMOS (59 classical phenotypes, 44 nonclassical phenotypes).Results: Classical phenotypes group has higher body-mass index (BMI), weight, waist circumference, waist height ratio, LH levels, TyG, LAP and VAI levels than non-classical phenotypes. In according to lipid profiles, classical PMOS group has more atherogenic trend. The difference between groups in TyG, LAP and VAI is eliminated after adjustment for BMI.Conclusion: Since BMI adjustment eliminates metabolic differences between classical and non-classical phenotypes, therapeutic interventions may focus on weight loss and obesity treatment for all phenotypes of PMOS.

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