DOI: 10.1126/science.1172257 ISSN:

The Genetic Structure and History of Africans and African Americans

Sarah A. Tishkoff, Floyd A. Reed, Françoise R. Friedlaender, Christopher Ehret, Alessia Ranciaro, Alain Froment, Jibril B. Hirbo, Agnes A. Awomoyi, Jean-Marie Bodo, Ogobara Doumbo, Muntaser Ibrahim, Abdalla T. Juma, Maritha J. Kotze, Godfrey Lema, Jason H. Moore, Holly Mortensen, Thomas B. Nyambo, Sabah A. Omar, Kweli Powell, Gideon S. Pretorius, Michael W. Smith, Mahamadou A. Thera, Charles Wambebe, James L. Weber, Scott M. Williams
  • Multidisciplinary

African Origins

The modern human originated in Africa and subsequently spread across the globe. However, the genetic relationships among the diverse populations on the African continent have been unclear. Tishkoff et al. (p. 1035; see the cover, published online 30 April) provide a detailed genetic analysis of most major groups of African populations. The findings suggest that Africans represent 14 ancestral populations. Populations tend to be of mixed ancestry which documents historical migrations. The data mainly support but sometimes challenge proposed relationships between groups of self-identified ethnicity previously hypothesized on the basis of linguistic studies. The authors also examined populations of African Americans and individuals of mixed ancestry from Cape Town, documenting the variation and origins of admixture within these groups.

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