DOI: 10.1001/jamasurg.2026.4783 ISSN: 2168-6254

The Future of Precision Hepatopancreatobiliary Surgery—Beyond Anatomy

Hassan Aziz, Timothy M. Pawlik

This Viewpoint proposes that the future of hepatopancreatobiliary surgery lies in layering molecular profiling, artificial intelligence, and liquid biopsy onto the traditional anatomic framework to individualize every phase of surgical care.

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