DOI: 10.56367/oag-052-12355 ISSN: 2516-3817
The cryptic drivers of neonatal brain damage and its similarities to adult neurodegenerative diseases
Lee J. MartinThe cryptic drivers of neonatal brain damage and its similarities to adult neurodegenerative diseases
Lee J. Martin helps us decode the cryptic biology of neonatal brain damage and its similarities to neurodegenerative diseases in adults. A form of neonatal brain damage called encephalopathy is a leading cause of newborn death and disability worldwide. Inadequate blood flow and oxygen delivery to the baby’s brain is a cause of the often-fatal crisis called clinically hypoxic-ischemic encephalopathy (HIE). For a long time, it has been known that specific regions of the brain and neural pathways are vulnerable in the infant brain depending on the onset and severity of physiological perturbation. This pattern is called selective vulnerability.