DOI: 10.1039/d5np00086f ISSN: 0265-0568
The complexity cliff in natural product discovery: why full automation remains elusive and the case for collaborative intelligence
Ran Lin, Chengzeng Zhou, Rongzhen Wu, Yinan Wang, Bin Wu, Zixin Deng, Jiangtao GaoNatural product discovery encounters a complexity cliff that defeats brute-force automation; collaborative intelligence, pairing machine throughput with human expertise, offers a more productive path than full autonomy.