Tear Film Lipid Layer Thickness and Its Impact on Dry Eye Severity in Saudi Arabian Glaucoma Patients: A Cross-sectional Analysis
Jawza Ali Almutairi, Jumana Radhi Alasbool, Sultan Alzahrani, Kawther Ibrahim Alhawsawi, Jomanah Khalid Aljohani, Ghadeer Abdullah I. Albalawi, Mostafa AlhodibiAbstract
Introduction:
The intersection of glaucoma and dry eye disease forms a significant area of concern in ophthalmology, given their prevalence and the profound impact they have on patients’ quality of life. This study delves into an intricate aspect of this intersection by exploring the correlation between tear film lipid layer thickness (TFLLT) and the severity of dry eye symptoms among Saudi Arabian patients with glaucoma. Anchoring its relevance in the broader context of ocular health, the research hypothesises that this correlation is influenced by various factors such as age, gender and the stage of glaucoma, aiming to enhance our understanding and inform more effective treatment strategies for these conditions.
Methods:
In this cross-sectional study, a structured questionnaire was distributed to glaucoma patients across different healthcare centres in Saudi Arabia between July and October 2023. The questionnaire was meticulously designed to gather comprehensive data on various aspects, including the severity of dry eye symptoms, the stage of glaucoma and the usage of contact lenses among the participants. This approach was chosen to obtain a clear picture of the relationship between TFLLT and dry eye severity in this specific patient group.
Results:
The study, encompassing a sample of 2010 participants, revealed noteworthy findings. One of the most significant outcomes was the established association between the usage of contact lenses and the severity of dry eye symptoms. The data indicated that those participants who wore contact lenses, either on a daily basis or occasionally, were more likely to report moderate to severe symptoms of dry eye, providing valuable insights into the factors exacerbating this condition among glaucoma patients.
Conclusion:
This research sheds light on the critical relationship between TFLLT and dry eye severity in patients with glaucoma. The findings underscore the importance of careful management of dry eye symptoms, especially in those who use contact lenses. The study not only contributes to our understanding of the pathophysiology of these ocular conditions but also opens avenues for future research and clinical interventions, aiming to improve the quality of life for patients suffering from these coexisting conditions.