Systematic Review on the Role of Salivary Protein in Oral Homeostasis

Background: Saliva serves plenty of critical functions. These encompass oral mucosa and enamel protection, antimicrobial action, nutrient facilitation, bodily washing, and buffering. Cross-sectional studies of human salivary proteins quickly reveal a great deal of variation in the levels of various proteins between individuals. Methods: PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), Science Direct, and Lilac were used to conduct a literature search Scopus using MeSH terms-role of salivary protein, oral homeostasis, the role of Saliva, and Oral health care. Of a total of 178articles screened, 83 were full-text articles assessed for eligibility and five were taken for qualitative analysis. This review was reported according to the PRISMA guidelines. Results: the role of salivary protein among different groups of people in all studies showed a statistically significant impact. And they are responsible for oral hygiene and oral homeostasis. Conclusion: salivary protein has a significant role in maintaining oral hygiene, antimicrobial action enamel protection and buffering action.