DOI: 10.1055/a-2157-5782 ISSN:

Synthetic Utility of N-Acylbenzotriazoles

MANGAL SINGH YADAV, Abhishek Gupta, Priyanka Bose, Anoop S Singh, Prabhu Prasad Mohapatra, Vinod K Tiwari
  • Organic Chemistry
  • Materials Science (miscellaneous)
  • Biomaterials
  • Catalysis

N-Acylbenzotriazoles are valuable synthons in organic synthesis. They are particularly used as acylating agents and an alternative to acyl chloride. They have been widely explored for a diverse range of applications. This review summarizes the methods for the preparation of N-acylbenzotriazole derivatives and their diverse applications in particular demonstration to serve as alternative acylating agents in organic transformations such as N-, O-, C-, and S-acylating agents for the convenient synthesis of a wide range of biologically important organic compounds. We also emphasize the synthesis of diverse compounds using benzotriazole ring cleavage (BtRC) methodology, including its pharmacophore study and some notable utilities as valuable starting materials, ligands, and intermediates in the field of organic synthesis.

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