DOI: 10.1039/d3bm01099f ISSN:
Synthetic lipo-polylysine with anti-cancer activity
Xuan Yi, Pengqi Wan, Wei Shen, Xiaonong Zhang, Peng Zhang, Chunsheng Xiao- General Materials Science
- Biomedical Engineering
A cationic lipo-polylysine C12-PLL13 can interact with negatively charged tumor cell membrane and induce cell necrosis by triggering membrane perforation and disintegration, offering a distinct therapeutic mechanism from traditional antitumor drugs.