DOI: 10.1039/d3bm01099f ISSN:

Synthetic lipo-polylysine with anti-cancer activity

Xuan Yi, Pengqi Wan, Wei Shen, Xiaonong Zhang, Peng Zhang, Chunsheng Xiao
  • General Materials Science
  • Biomedical Engineering

A cationic lipo-polylysine C12-PLL13 can interact with negatively charged tumor cell membrane and induce cell necrosis by triggering membrane perforation and disintegration, offering a distinct therapeutic mechanism from traditional antitumor drugs.

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