DOI: 10.1039/d6ra07420k ISSN: 2046-2069
Synthesis, RSM-based optimization, biological evaluation, and molecular modeling of novel ( R )-carvone-derived isoxazole derivatives as antibacterial agents
Nora M. Farhan, Rawiyah A. Alkahtani, Jehan Y. Al-Humaidi, Yousef E. Mukhrish, Bharath Kumar Chagaleti, Rachid Azzallou, Ali Oubella, Reda A. HaggamSynthesis, RSM-based optimisation, and antibacterial evaluation of novel ( R )-carvone-derived isoxazole derivatives (3–5) supported by network pharmacology, ADMET, molecular docking, and dynamics to analyse their potential targets and interactions.