DOI: 10.1002/ejoc.70763 ISSN: 1434-193X

Synthesis of 1,4‐Dihydroquinolines via [4 + 2] Annulation of Aminobenzylphosphonium Salts With Ethyl Benzoylacetate Derivatives

Yun‐Xing Zhong, Zhen‐Zhong Zhang, Liang Cui, Shao‐Wei Zhou, Ping‐Gui Li, Liang‐Hua Zou

A novel synthetic strategy for the preparation of 1,4‐dihydroquinolines has been developed through [4 + 2] annulation of aminobenzylphosphonium salts (ABPS) with ethyl benzoylacetate derivatives. This protocol features mild reaction conditions, readily available starting materials, broad substrate scope, and good to excellent yields.

More from our Archive