DOI: 10.1039/d6qo00155f ISSN: 2052-4129
Synthesis of α-quaternary amino acid derivative via 1,2-rearrangement of ammonium ylide
Ao Huang, Rui Li, Zhenxiu Huang, Lei Wang, Xin Wang, Kaixin Du, Shi TangAlthough α-quaternary amino acids often exhibit notable bioactivity, their synthesis has received comparatively less attention, primarily due to the considerable steric hindrance posed by the quaternary center.