DOI: 10.1039/d6ra04078k ISSN: 2046-2069

Synthesis, characterization, crystal structures, antitumor activity, and computational study of novel thiosemicarbazone derivatives from thiazol-2/5-carbaldehyde

Wilfredo Hernández, Fernando Carrasco, Abraham Vaisberg, Evgenia Spodine, Maik Icker, Harald Krautscheid, Christian Jänke, Lothar Beyer, Osvaldo Yáñez

New thiazol-carbaldehyde thiosemicarbazone derivatives were synthesized. Compounds 3 and 6 showed greater cytotoxicity than the other tested compounds against the MCF-7 cell line.