DOI: 10.1039/d6ra08884h ISSN: 2046-2069

Synthesis and preclinical evaluation of a novel 2-[ 18 F]fluoropyridine-bearing rhodamine for myocardial perfusion imaging with PET

Maya Mahmood, Emily Murrell, Seniha Ozyuncu, Junchao Tong, Angelina Lui, James A. H. Inkster

A [ 18 F]fluoropyridine-bearing rhodamine has been designed for myocardial perfusion imaging. Straightforward synthesis of precursors and automated radiolabeling methods permitted the evaluation of [ 18 F]Rho6G-DEG-Py-F uptake into rat hearts with PET.

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