DOI: 10.1039/d6ra00504g ISSN: 2046-2069

Synergistic surface modification of zirconia nanotubes with silver and hydroxyapatite for enhanced early-stage cytocompatibility: ToF-SIMS insights into fibronectin adsorption

Gabriel Onyenso, Lu Yuan, Nastaran Farahbakhsh, Setareh Orangpour, Paola Carolina Zamudio Franco, Johannes Schmitt, Carsten Engelhard, Christian Pritzel, Henny C. van der Mei, Manuela S. Killian
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Hydroxyapatite modification of Ag-zirconia nanotubes enhances fibronectin adsorption, identified by unique RGD fragments in ToF-SIMS, while preserving the open nanotubular morphology, improves early-stage osteoblast adhesion and cytocompatibility.

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