DOI: 10.1039/d5fo04709a ISSN: 2042-6496
Supporting joint health through the gut-immune axis: squalene-based multiple emulsions enhance oral delivery of undenatured collagen type II for immune tolerance
Jing Wang, Chen Yuan, Qin Xia, Tingting Liu, Shunjie Qin, Daiwen Zheng, Zuoyan She, Bo Peng, Junfeng Hong, Bohui XuW/O/W multiple emulsions encapsulate UC-II, protect it from gastrointestinal degradation, enhance uptake by Peyer's patches, modulate the gut-immune axis to promote immune balance and induce tolerance, thereby effectively supporting joint health.