SUPC-02 DEPRESSION IN METASTATIC SPINE DISEASE: PREVALENCE IN A SURGICAL COHORT
Dalton Tara, Ellen O’Callaghan, Dotun Bello, Dana Rowe, Seeley Yoo, Michael Goodin, Kerri-Anne Crowell, Margaret Johnson, Melissa Erickson, C Rory GoodwinAbstract
Introduction
Major depressive disorder (MDD) occurs at rates up to five times higher in cancer patients when compared to the general population. As even subclinical levels of depression can worsen outcomes and lead to increased mortality through both non-adherence and psychosocial stressors, we sought to evaluate the rates of self-reported depression in patients with metastatic spine disease (MSD).
Methods
A retrospective study evaluated surgical MSD patients at a single large academic center between 2015 and 2023. The overall prevalence of depression was identified as the proportion of patients that reported depression at any time point during their perioperative period. Prevalence was also evaluated at baseline (defined as the closest recorded timepoint prior to surgery within 30 days preoperative), 30 days pos-op, and at 90 days post-op.
Results
Of 342 patients, 33.3% reported depression at least once during the perioperative period. Depression rates across the cohort did not vary significantly at each time point, with 17.4% reporting depression at baseline, 17.3% at 30 days post-op, and 14.1% at 90 days post-op. When comparing rates of depression in each sociodemographic subgroup, there were no significant differences between white versus nonwhite patients, females versus males, or married versus non-married patients. This study is the first to demonstrate self-reported depression rates in MSD patients during the perioperative period.
Conclusion
Self-reported depression rates are prevalent in the patients undergoing surgery for MSD and do not vary significantly by sociodemographic factors or perioperative time point. Future prospective studies may elucidate the presence of predictors of depression and further delineate if there are risk factors in particular patients that can be accounted for and supported in perioperative care.