DOI: 10.1001/jamapsychiatry.2026.3384 ISSN: 2168-622X

Suicide as System Collapse and the Need for Deep Phenotyping

Gregory Witkop, Richard J. Davidson, Kerry J. Ressler, Matthew K. Nock

This Viewpoint suggests that the field of psychiatry would benefit from a prioritization of the study of suicidal behavior at the point of system collapse, where signals of biological dysregulation are most dense and intense.

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