DOI: 10.1192/j.eurpsy.2026.10810 ISSN: 0924-9338

Substance Use Disorders and Psychiatric Comorbidity

K. Taleb, F. Laajili, H. Ballouk, Z. Bencharfa, F. El Omari

Introduction

Substance use disorders (SUDs) are often associated with other mental disorders—psychotic, mood, or anxiety—complicating treatment and worsening clinical and social outcomes.

Objectives

To describe the main psychiatric comorbidities among patients with SUDs and examine their relationship with substance type.

Methods

A retrospective descriptive study based on clinical records of patients consulting for SUDs. Collected data included sociodemographic profile, substances used, psychiatric diagnoses, and treatments.

Results

Results (N = 102):

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Gender: predominantly male (~90%).

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Age: mostly 20–40 years.

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Main substances: tobacco (85%), cannabis (70%), alcohol (56%).

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Comorbid disorders: psychotic (45%), mood (30%), anxiety (15%), personality (10%).

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Polysubstance use: >50% of patients.

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Treatments: antipsychotics (79%), antidepressants (55%), anxiolytics (38%).

Conclusions

SUDs are commonly associated with severe psychiatric comorbidities. Systematic screening and a dual-diagnosis approach are key to enhancing prognosis and patient reintegration.

Disclosure of Interest

None Declared

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