DOI: 10.1002/slct.75043 ISSN: 2365-6549
Study of the Features of Interaction of Semicarbazide With Dialkylchloroethynyl Phosphonates
Elizaveta Gerasimova, Dmitry Egorov, Anastasia Egorova, Ekaterina Chernova, Nikita Serov, Timur GimadievABSTRACT
The reaction of semicarbazide with dialkyl chloroethynyl phosphonates proceeds with exclusive chemo‐ and regioselectivity to afford phosphonylated 1,3,4‐oxadiazoles, as unambiguously confirmed by x‐ray crystallography. Quantum chemical calculations were performed to rationalize the observed selectivity and elucidate the reaction mechanism.