STUDY OF CORRELATION BETWEEN THROMBOCYTOPENIAAND FUNGAL URINARY TRACT INFECTION IN NEONATES
Shahrukh Khan- General Medicine
- Microbiology (medical)
- Immunology
- Immunology and Allergy
- General Agricultural and Biological Sciences
- General Earth and Planetary Sciences
- General Environmental Science
- Automotive Engineering
- Industrial and Manufacturing Engineering
- General Medicine
- General Medicine
- General Medicine
- General Medicine
Background: Thrombocytopenia is thought to be as an early marker of infection in neonate. Fungal infection is associated with greater degree of thrombocytopenia as compared to bacterial infection ( either gram positive or gram negative organisms). Urine Culture is less invasive and may be more safer and can help in early diagnosis of fungal infection whenever there is thrombocytopenia and other clinical features of fungal infection, specially preterm neonates admitted in NICU. Aims and Objectives: To study the correlation of thrombocytopenia in neonate and fungal Urinary tract infection. Materials and Methods:This retrospective study was conducted from 1st July 2022 to 31st December 2022 in the NICU of MGM medical college and M.Y.hospital, Indore, Madhyapradesh. Out of 131 urine samples sent, 49 neonates with UTI were included and grouped into fungal and bacterial urinary tract infection as per the growth of organisms. Urine cultures were done on Automated BacT/Alert 3 D Rapid Bacterial Culture System. Platelet count was measured by automated cell counter and on peripheral smear by Pathologist. Thrombocytopenia was dened as platelet count less than 150000/mm3. The data was analyzed using Chi Square test. Results: 33 (67%) and 16 (33%) cultures were positive for bacterial and fungal UTI respectively. Thrombocytopenia seen in 14(87.5%) fungal urinary tract infection as compared to 05(15.15%) bacterial urinary tract infection group which was statistically signicant. (P<0.05). Conclusion: Thrombocytopenia was signicantly associated with fungal urinary tract infection in neonate and can be taken as marker of fungal infection.