Study of Clinicopathological Correlation of Endometrium in Abnormal Uterine Bleeding
Priyanka Ramesh Deshmukh, Sonal Ashutosh Bhuyar, Pushpa Shankarrao Junghare
A
BSTRACT
Background:
Abnormal uterine bleeding (AUB) is considered one of the most common and challenging problems presenting to the gynecologist. It is responsible for as many as one-third of all outpatient gynecological visits. AUB accounts for 33% of outpatient referrals. AUB interferes with woman’s physical, social, emotional, and maternal quality of life. Histopathological evaluation of endometrial samples is crucial for diagnosing the underlying causes of AUB.
Aims and Objectives:
To analyze the clinicopathological correlation of endometrial findings in women presenting with AUB, focusing on histopathological patterns and associated clinical features.
Materials and Methods:
A cross-sectional study was conducted over 18 months at a tertiary healthcare center. The study included female patients aged over 35 years presenting with complaints of AUB. Endometrial samples were obtained through dilatation and curettage (D and C) and analyzed histopathologically. Clinical data were collected via structured interviews and clinical examinations.
Results:
The majority of patients were aged between 41 and 45 years (31.8%), with a mean age of 44.8 years. Menorrhagia was the most common bleeding pattern (57.1%), followed by menometrorrhagia (30.2%) and postmenopausal bleeding (12.7%). Endometrial hyperplasia without atypia was the predominant histopathological finding (63.3%), followed by proliferative phase (17.1%) and secretory phase (14.3%). Endometrial carcinoma was identified in 3.7% of cases.
Conclusion:
Histopathological evaluation is essential in diagnosing the causes of AUB. Endometrial hyperplasia without atypia is the most common finding with clinical symptom Menorrhagia, especially in perimenopausal women.