DOI: 10.1039/d3cs00972f ISSN: 0306-0012
Strategies for designing biocatalysts with new functions
Elizabeth L. Bell, Amy E. Hutton, Ashleigh J. Burke, Adam O’Connell, Amber Barry, Elaine O’Reilly, Anthony P. Green- General Chemistry
Enzymes can be optimized to accelerate chemical transformations via a range of methods. In this review, we showcase how protein engineering and computational design techniques can be interfaced to develop highly efficient and selective biocatalysts.