DOI: 10.1039/d6qo00617e ISSN: 2052-4129

Stereoselective construction of cyclic quaternary stereocenters by Prins cyclization with ketones

Laura F. Peña, Lucía G. Parte, Carlos Díez-Poza, Asunción Barbero

A general Prins-type cyclization with ketone substrates that enables the efficient and stereoselective construction of tetrahydropyrans bearing quaternary carbon centers is described.

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