DOI: 10.1039/d3ob01098h ISSN:

Squaramide-catalyzed asymmetric regioselective allylic alkylation of 4-aminopyrazolones with Morita–Baylis–Hillman carbonates

Aiqi Xue, Shiqiang Wei, Xingfu Wei, Yue Huang, Jingping Qu, Baomin Wang
  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

An asymmetric regioselective allylic alkylation of 4-aminopyrazolones with various MBH carbonates has been established. The products were further derivatized by [3 + 2] cycloadditions with 1,3-dipoles providing bi-heterocyclic structures.

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