DOI: 10.1039/d4ra08100e ISSN: 2046-2069
Spatially-resolved characterization of the metabolic and N-glycan alterations in colorectal cancer using matrix-assisted laser desorption/ionization mass spectrometry imaging
Yaqi Zhang, Qiangjun Chen, Lei Wang, Haoyuan Geng, Zihan Zhu, Cancan Lv, Yisheng Zhao, Xiao Wang, Chenglong Sun, Panpan Chen, Chao ZhangThe multi-omics approach combining MSI-based metabolomics and N-glycomics visualized spatial distributions of metabolites and N-glycans in heterogeneous colorectal cancer tissues.