SP 3.07 Outcomes of Colorectal Cancer Polypectomy in Bowel Cancer Screening Program Compared to Polypectomies in Symptomatic Presentation

Aims

Bowel cancer screening program is offered to people aged 50 to 74 every 2 years. This study aimed to compare outcomes and survival rates of patients who underwent polypectomy for colorectal cancers referred through this pathway to symptomatic polypectomies.

Methods

Retrospective comparative study for 10 years between 2015 and 2024.

Results

There was a total of 52 patients from the BSCP group who had cancer in the polyp and 40 in the symptomatic group. There were differences in population with median BSCP age being 67 years and 75 years in symptomatic group, more males (39,73.5%) in the BSCP group compared to (21,52.5%) in the symptomatic group.

Margin status differed by detection pathway:(p=0.06) with BSCP having resection status R0:17(32%), R1:18(34%), Rx:18(34%) and Symptomatic pathway: R0:9(23%), R1:22(55%), Rx: 9(23%). Higher incidence of well to moderately differentiated tumours (62.2%) in the BSCP pathway as compared to symptomatic (42.5%) p=0.01. Lymphovascular invasion was detected in 6(11.3%) of BCSP vs 10(25%) of symptomatic polyps p=0.04.

Of the BSCP group 12(23%) went on to have bowel resection compared to 7(17.5%) of the symptomatic group. They were followed up for a median of 2.8 years and a Kaplan Meiers graph was plotted which showed the BSCP group to have a better survival rate as compared to symptomatic group.

Conclusions

The study shows that patients who are found to have colorectal cancer in polyps resected through the BSCP referrals have favourable outcomes and long-term survival rates.