DOI: 10.1093/bjs/znag087.012 ISSN: 0007-1323

SP 1.06 Clinical Outcomes Following 108 Primary Ventral and Incisional Hernia Repair with OviTex Mesh - A Single-Centre Experience

Bharti Kewlani, Mary Fenita Suresh, Raimundas Lunevicius

Abstract

Aims

Polypropylene-reinforced OviTex mesh (OviTex-P) was developed to address limitations of synthetic and biologic meshes in abdominal wall reconstruction. This study evaluated outcomes following ventral and incisional hernia repair using OviTex-P.

Methods

A retrospective cross-sectional review of prospectively collected cases (June 2021–October 2025) was conducted at a university hospital. Open or burst abdomen closure cases were excluded. Data collected included demographics, comorbidities, Ventral Hernia Working Group (VHWG) classification, operative details, and postoperative outcomes. Univariate analysis was performed using Fisher’s exact test to assess associations with hernia recurrence.

Results

One hundred and eight patients were included (male: female ratio 7:5; mean age 59.6 ± 14.7 years; mean BMI 33.8 ± 10.3). Most underwent open repair (92.6%), and 80.5% were VHWG grade 1/2. Mesh and defect sizes ranged from 32–1000 cm² and 4–551 cm². Postoperative complications included seroma in 22 patients (20.4%) and infection in 21 (19.4%), of which 13 (12.0%) were deep infections; one patient (0.9%) required mesh explantation for chronic infection. Median length of stay was 5 days (IQR 1–7), with median follow-up of 19 months (IQR 5.5–31). Ten patients (9.3%) developed recurrence; five had undergone component separation. Hernia recurrence was significantly associated with higher VHWG grade (grade 3/4 vs 1/2; OR 5.13, 95% CI 1.33-19.78; p=0.023), with no association observed for component separation, previous abdominal surgery, or BMI >30.

Conclusions

OviTex-P demonstrated favourable outcomes in ventral and incisional hernia repair, with recurrence associated with higher VHWG grade.

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