DOI: 10.1152/ajprenal.00079.2026 ISSN: 1931-857X

Skeletal muscle adaptation to home-based exercise in chronic kidney disease

Sarah E. Brashear, Anas Mohamed Sulthan, Denise Chan, Vishal Rao, Gwenaelle Begue, Armin Ahmadi, Tae Youn Kim, Jennifer E. Norman, Usman Rehman, Thomas Jue, Craig M. McDonald, Jorge L. Gamboa, Baback Roshanravan, Lucas R. Smith

This study investigates the impact of a home-based, video-monitored 12-wk exercise program, consisting of both endurance and resistance exercise, on skeletal muscle structural remodeling in persons with chronic kidney disease. We found this program increased capillaries and decreased fibroadipogenic progenitors after exercise.

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