DOI: 10.1126/science.1245316 ISSN:
Single-Cell RNA-Seq Reveals Dynamic, Random Monoallelic Gene Expression in Mammalian Cells
Qiaolin Deng, Daniel Ramsköld, Björn Reinius, Rickard Sandberg- Multidisciplinary
Expressing One Allele at a Time
Although genetic traits are often dominant or recessive, the impact of the same heterozygous genotype can vary quite a bit between individuals.
Deng
et al.
(p.