DOI: 10.5694/mja2.70327 ISSN: 0025-729X
Short‐Term Adverse Events Following Recombinant Zoster Vaccination in Older Adults in Australia: A Survey Study Comparing Dose 1 and Dose 2 and Influence of Dose Interval
Lucy Dawes, Thuy Nguyen, Kristine Macartney, Lucy DengABSTRACT
Self‐reported adverse events following first and second recombinant zoster vaccination (RZV) doses in older adults ( n = 41,069) collected through AusVaxSafety were analysed. Adverse event rates were higher following Dose 2 (54%; 95% CI, 53%–54%) than after Dose 1 (45%; 95% CI, 45%–46%), particularly with 3–6‐ and 7–9‐month dose intervals, although medical review rates remained low (1.1%; 95% CI, 1.0%–1.2%), suggesting RZV is reactogenic but with no serious outcomes.