Shifting the limits in wheat research and breeding using a fully annotated reference genome
, Rudi Appels, Kellye Eversole, Nils Stein, Catherine Feuillet, Beat Keller, Jane Rogers, Curtis J. Pozniak, Frédéric Choulet, Assaf Distelfeld, Jesse Poland, Gil Ronen, Andrew G. Sharpe, Omer Barad, Kobi Baruch, Gabriel Keeble-Gagnère, Martin Mascher, Gil Ben-Zvi, Ambre-Aurore Josselin, Axel Himmelbach, François Balfourier, Juan Gutierrez-Gonzalez, Matthew Hayden, ChuShin Koh, Gary Muehlbauer, Raj K. Pasam, Etienne Paux, Philippe Rigault, Josquin Tibbits, Vijay Tiwari, Manuel Spannagl, Daniel Lang, Heidrun Gundlach, Georg Haberer, Klaus F. X. Mayer, Danara Ormanbekova, Verena Prade, Hana Šimková, Thomas Wicker, David Swarbreck, Hélène Rimbert, Marius Felder, Nicolas Guilhot, Gemy Kaithakottil, Jens Keilwagen, Philippe Leroy, Thomas Lux, Sven Twardziok, Luca Venturini, Angéla Juhász, Michael Abrouk, Iris Fischer, Cristobal Uauy, Philippa Borrill, Ricardo H. Ramirez-Gonzalez, Dominique Arnaud, Smahane Chalabi, Boulos Chalhoub, Aron Cory, Raju Datla, Mark W. Davey, John Jacobs, Stephen J. Robinson, Burkhard Steuernagel, Fred van Ex, Brande B. H. Wulff, Moussa Benhamed, Abdelhafid Bendahmane, Lorenzo Concia, David Latrasse, Jan Bartoš, Arnaud Bellec, Hélène Berges, Jaroslav Doležel, Zeev Frenkel, Bikram Gill, Abraham Korol, Thomas Letellier, Odd-Arne Olsen, Kuldeep Singh, Miroslav Valárik, Edwin van der Vossen, Sonia Vautrin, Song Weining, Tzion Fahima, Vladimir Glikson, Dina Raats, Jarmila Číhalíková, Helena Toegelová, Jan Vrána, Pierre Sourdille, Benoit Darrier, Delfina Barabaschi, Luigi Cattivelli, Pilar Hernandez, Sergio Galvez, Hikmet Budak, Jonathan D. G. Jones, Kamil Witek, Guotai Yu, Ian Small, Joanna Melonek, Ruonan Zhou, Tatiana Belova, Kostya Kanyuka, Robert King, Kirby Nilsen, Sean Walkowiak, Richard Cuthbert, Ron Knox, Krysta Wiebe, Daoquan Xiang, Antje Rohde, Timothy Golds, Jana Čížková, Bala Ani Akpinar, Sezgi Biyiklioglu, Liangliang Gao, Amidou N’Daiye, Marie Kubaláková, Jan Šafář, Françoise Alfama, Anne-Françoise Adam-Blondon, Raphael Flores, Claire Guerche, Mikaël Loaec, Hadi Quesneville, Janet Condie, Jennifer Ens, Ron Maclachlan, Yifang Tan, Adriana Alberti, Jean-Marc Aury, Valérie Barbe, Arnaud Couloux, Corinne Cruaud, Karine Labadie, Sophie Mangenot, Patrick Wincker, Gaganpreet Kaur, Mingcheng Luo, Sunish Sehgal, Parveen Chhuneja, Om Prakash Gupta, Suruchi Jindal, Parampreet Kaur, Palvi Malik, Priti Sharma, Bharat Yadav, Nagendra K. Singh, Jitendra P. Khurana, Chanderkant Chaudhary, Paramjit Khurana, Vinod Kumar, Ajay Mahato, Saloni Mathur, Amitha Sevanthi, Naveen Sharma, Ram Sewak Tomar, Kateřina Holušová, Ondřej Plíhal, Matthew D. Clark, Darren Heavens, George Kettleborough, Jon Wright, Barbora Balcárková, Yuqin Hu, Elena Salina, Nikolai Ravin, Konstantin Skryabin, Alexey Beletsky, Vitaly Kadnikov, Andrey Mardanov, Michail Nesterov, Andrey Rakitin, Ekaterina Sergeeva, Hirokazu Handa, Hiroyuki Kanamori, Satoshi Katagiri, Fuminori Kobayashi, Shuhei Nasuda, Tsuyoshi Tanaka, Jianzhong Wu, Federica Cattonaro, Min Jiumeng, Karl Kugler, Matthias Pfeifer, Simen Sandve, Xu Xun, Bujie Zhan, Jacqueline Batley, Philipp E. Bayer, David Edwards, Satomi Hayashi, Zuzana Tulpová, Paul Visendi, Licao Cui, Xianghong Du, Kewei Feng, Xiaojun Nie, Wei Tong, Le Wang- Multidisciplinary
Insights from the annotated wheat genome
Wheat is one of the major sources of food for much of the world. However, because bread wheat's genome is a large hybrid mix of three separate subgenomes, it has been difficult to produce a high-quality reference sequence. Using recent advances in sequencing, the International Wheat Genome Sequencing Consortium presents an annotated reference genome with a detailed analysis of gene content among subgenomes and the structural organization for all the chromosomes. Examples of quantitative trait mapping and CRISPR-based genome modification show the potential for using this genome in agricultural research and breeding. Ramírez-Gonzálezet al.exploited the fruits of this endeavor to identify tissue-specific biased gene expression and coexpression networks during development and exposure to stress. These resources will accelerate our understanding of the genetic basis of bread wheat.
Science, this issue p.