Selective SNH Alkylamination of 3(5,6,7,8)‐Nitroquinoline and 5‐Nitroisoquinoline in an Aqueous Medium

Direct oxidative SNH alkylamination of 3‐, 5‐, 6‐, 7‐, 8‐nitroquinolines and 5‐nitroisoquinoline in an aqueous solution of an aliphatic amines gives rise to the corresponding alkylamino and dialkylamino derivatives of these nitrohetarenes. The nitro group solely dictates the regioselectivity of reactions. The antibacterial activity of some of them has been studied