DOI: 10.1111/cea.70382 ISSN: 0954-7894

GWAS of Second‐Generation Antihistamine Use: Locus Specificity and Highlighted Signalling Pathways

M. Niemi, S. Ruotsalainen, E. Saarentaus, I. Vähätalo, F. FinnGen, I. Starskaia, T. Harju, M. Pelkonen, T. Feuth, P. Kauppi, J. Partanen, R. Lahesmaa, V. Hytönen, A. Palotie, H. Kankaanranta, T. Laitinen

Summary

Four of 67 loci were specific to antihistamine use; most overlapped inflammatory disease susceptibility.

Genetic variation enriched in IL‐2 cytokine, JAK–STAT pathway genes shared by allergy and autoimmunity.

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