DOI: 10.1039/d6fo04156f ISSN: 2042-6496

Schaftoside, a functional flavonoid from fenugreek ( Trigonella foenum-graecum L.), alleviates depression and cognitive deficits via the microbiome–gut–brai

Yu Dai, Pei Song, Cuilin Cheng, Li Cheng, Cuihong Dai, Weihong Lu

Schaftoside, the major flavonoid of fenugreek seeds, ameliorates stress-induced depression by suppressing Bacteroides , enriching Butyricicoccus , and restoring the intestinal barrier, typtophan metabolism, and hippocampal neurotransmitters.

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