Scalable Manufacturing of Amino Acid‐Based Piezoelectric Biocrystal Films

ABSTRACT

Glycine is a promising piezoelectric biocrystal owing to its excellent biocompatibility, strong piezoelectric response, and high crystallinity. Recent discovery of polymer‐directed crystallization of glycine in an aqueous environment offers the feasibility for continuous manufacturing of this biocrystal film at the industry‐relevant level. In this paper, we report continuous production of glycine‐PVA piezoelectric biocrystal thin films by adapting a commercial polymer manufacturing apparatus with a uniform sandwiched microstructure. By tuning the feeding rate and solvent evaporation dynamics, a stable crystallization front is maintained, enabling continuous film growth over lengths of tens of centimeters, which largely matches a numerical kinetic model. The as‐produced films exhibit sandwiched microstructure, with uniform thickness, grain size, and piezoelectric coefficient across the entire area. Fifty‐six piezoelectric nanogenerator devices were fabricated on a single large‐scale film, demonstrating the feasibility of high‐throughput device production. This work establishes a stable and industrially viable strategy for the large‐scale manufacturing of piezoelectric biocrystal films, offering significant potential for mass production of biocompatible piezoelectric devices.