DOI: 10.1093/ced/llag424 ISSN: 0307-6938

Safety and effectivity of dupilumab in transplant recipients with severe atopic dermatitis: A multicenter case series

Raquel Domínguez-López, Mónica Munera Campos, Francisco Navarro Triviño, Trinidad Montero Vílchez, Constanza Riquelme-Mc Loughlin, Rubén Barros Tornay, Álvaro González Cantero, Emilio Berná-Rico, Enrique Gómez de la Fuente

This multicenter retrospective case series evaluated the safety and effectiveness of dupilumab in nine solid organ transplant recipients with severe atopic dermatitis. Treatment resulted in rapid and sustained clinical improvement in most patients, with significant reductions in disease severity, pruritus, and quality-of-life impairment, and minimal adverse events. Importantly, no graft dysfunction or need for immunosuppressive adjustment was observed, supporting dupilumab as a promising therapeutic option in this high-risk population.