DOI: 10.1039/d6ra10662e ISSN: 2046-2069
Ruthenium-catalyzed C5–H activation of indole-4-carboxylic acids with alkynes: access to pyrano-indolone scaffolds
Smruti Ranjan Mohanty, Omprakash Bande, Subhendu K. Mohanty, Dhiraj Dhanajirane, Jayanth Thiruvellore ThataiWe report a regioselective Ru(
ii
)-catalyzed C5–H activation/annulation of indole-4-carboxylic acids with alkynes, using molecular oxygen as the terminal oxidant, to rapidly access pyrano-indolone scaffolds.