DOI: 10.1039/d6ob01308b ISSN: 1477-0520

Ruthenium-catalyzed asymmetric transfer hydrogenation of [2.2]paracyclophanecarboxaldehydes via kinetic resolution

Yu Yang, Jia-Xuan Wang, Hao-Dong Chen, Chang Chen, Yong-Gui Zhou, Bo Wu, Chang-Bin Yu

A Ru-catalyzed kinetic resolution of [2.2]paracyclophanecarboxaldehydes via asymmetric transfer hydrogenation was developed with excellent selectivity factors, and could be operated under decagram scale with high activity and enantioselectivity.