Role of Individualized Homeopathic Medicines in Improving the Symptoms of Erectile Dysfunction in Adults: An Open-label, Single-arm, Clinical trial
Pritom Patra, Sangita Saha, Subhasish Ganguly, Pulakendu Bhattacharya, Satyajit Naskar, Preeti Bhandari, Anil Kumar Mandi, Munmun Koley, Subhranil Saha
A
BSTRACT
Aim:
Erectile dysfunction (ED) is a prevalent sexual health issue affecting up to 31% of men, with an anticipated 322 million cases projected worldwide by 2025. While conventional therapies may cause adverse effects and provide temporary symptomatic relief, homeopathy may offer a cost-effective and safer therapeutic option. The investigators aimed to detect the role of individualized homeopathic medicines (IHMs) in the treatment of ED in adults.
Methods:
A nonrandomized, noncontrolled, single-arm, clinical study was conducted on 36 participants with ED with the intervention of IHMs along with concomitant care. The primary outcome was the International Index of Erectile Function (IIEF); the secondary outcomes were the Male Sexual Health Questionnaire (MSHQ) and the Measure Yourself Medical Outcome Profile-2 (MYMOP-2) profile scores, assessed at baseline and monthly, up to 3 months. An intention-to-treat approach was applied to detect intra-group changes.
Results:
After 3 months of intervention, intra-group changes were statistically and clinically significant (all
Conclusion:
IHMs resulted in a significant improvement in ED over 3 months of intervention. Further exploration is warranted with randomized trials.
Trial Registration:
CTRI/2023/03/050318.