DOI: 10.4103/ija.ija_890_26 ISSN: 0019-5049

Role of direct intraoperative ultrasound-guided renal resistive index and its association with postoperative acute kidney injury in patients undergoing abdominal vascular surgeries: A prospective cohort study

Sachin S. P. Bhardwaj, Tanvir Samra, Nitika Goel, Ajay Savlania, Harish Bhujade, Ganesh K. Munirathinam

ABSTRACT

Background and Aims:

Acute kidney injury (AKI) is a major complication following abdominal vascular surgery, and current diagnostic markers often detect injury only after significant renal damage has occurred. Doppler-derived renal resistive index (RRI) is a promising real-time marker of renal perfusion. This study evaluated direct intraoperative ultrasound (DIOUS)-guided RRI measurement for assessing postoperative AKI in open abdominal vascular surgery.

Methods:

In this prospective study, 40 adults undergoing open abdominal vascular procedures were enroled. RRI was measured at four timepoints: preoperatively; intraoperatively, 30 minutes after aortic declamping, using DIOUS; and postoperatively at 12 and 24 hours using transabdominal Doppler ultrasonography. AKI was defined using Kidney Disease: Improving Global Outcomes creatinine-based criteria.

Results:

Postoperative AKI developed in 50% of patients. Mean DIOUS-guided RRI measured 30 minutes after declamping was higher in patients who developed AKI than in those who did not (0.74 ± 0.05 vs. 0.69 ± 0.04; P = 0.003). Receiver operating characteristic analysis identified an exploratory, internally derived intraoperative RRI cut-off of 0.71, predicting postoperative AKI with 80% sensitivity and 70% specificity [area under curve 0.783; 95% confidence interval (CI) 0.639–0.927]. The odds of developing AKI increased by 33% for every 0.01-unit increase in intraoperative RRI (odds ratio 1.33; 95% CI 1.03–1.71; P = 0.026).

Conclusion:

DIOUS-guided RRI measurement is a feasible method for real-time assessment of renal haemodynamics during open abdominal vascular surgery. The association between intraoperative RRI and postoperative AKI suggests this technique may complement perioperative renal risk assessment and support early kidney-protective interventions, pending validation in larger studies.

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