DOI: 10.1039/d6ra06414k ISSN: 2046-2069

Rhenium tricarbonyl coumarin complexes as promising anti-MRSA candidates targeting bacterial biofilms and systemic infection, with reduced resistance development

Fatlinda Rahmani Mustafaj, Gozde Demirci, Nikola Plackic, Bettina Tran, Aurelien Crochet, Youri Cortat, Nemanja Stanisavljevic, Stefan Salentinig, Aleksandar Pavic, Fabio Zobi

A new family of rhenium tricarbonyl complexes eradicates MRSA in vivo , disrupts mature biofilms, and shows no detectable resistance development.