DOI: 10.36106/ijsr/0407141 ISSN:


Monali D. Makasana, Jyoti Gadhavee, Krishna K. Patel, Minesh B Gandhi, Anjali Goyal, Cherry K Shah
  • General Medicine
  • Microbiology (medical)
  • Immunology
  • Immunology and Allergy
  • General Agricultural and Biological Sciences
  • General Earth and Planetary Sciences
  • General Environmental Science
  • Automotive Engineering
  • Industrial and Manufacturing Engineering
  • General Medicine
  • General Medicine
  • General Medicine
  • General Medicine

Castleman disease is characterized by proliferation of lymphoid tissue. Clinically it presents in two forms either a unicentric or multricentric. Most common location is mediastinum, neck, axilla and pelvis. Unicentric retroperitoneal location is rare. Three general histologic patterns are seen in Castleman disease: (1) Hyaline vascular (2) hypervascular (3) Plasma cell rich, mainly seen in patients with multicentric disease. 49 Case report year female came to our hospital with complaint of generalized abdominal pain since 1.5 months. Physical examination was unremarkable. No history of any oswellings in any part of her body. HIV, HBsAg and Anti-HCV antibodies were negative. Other investigations including hematological and biochemical tests were normal. The chest X-ray did not reveal any mediastinal mass. The CT IVP ndings are suggestive of a well dened intensely homogenously enhancing soft tissue density lesion in anterior para renal space on left side with adjacent fat stranding and enlarged lymph nodes. Possibility of 1) arteriovenous malformation 2) Reactive lymphoproliferative disease 3) Castleman disease. Complete surgical excision was done. Pathological ndings showed localized hyaline vascular type of Castleman's disease.

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